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Explore vitiligo research with clear summaries, study limitations and direct references.
6 verified research storiesEnglish & ItalianContext imageA phase 2 trial studied whether immune signals change alongside repigmentation during ruxolitinib treatment. Sixty adults were assigned to ruxolitinib cream or vehicle for 24 weeks, followed by active treatment.
The Journal of investigative dermatology
Context imageTwo French centres followed 51 people receiving a combined treatment programme and compared groups defined by disease duration and activity. At six months, a 75% improvement in the Vitiligo Extent Score was reported in 46% of the recently diagnosed group, compared with 16% and 0% in the longer-duration groups.
Journal of the European Academy of Dermatology and Venereology : JEADV
Context imageResearchers analysed blood and skin blister fluid from 30 people beginning standard care for vitiligo. More than 5,000 proteins were screened at the start and after three months.
The Journal of investigative dermatology
Context imageThis publication describes the design of the Tranquillo phase 3 programme investigating oral ritlecitinib for nonsegmental vitiligo. The programme includes placebo-controlled studies, an extension study and planned analyses of repigmentation, safety and response durability.
Dermatology and therapy
Original study figureA genetics study compared early and later onset vitiligo using existing association datasets, immune-cell information and exploratory blood analyses. The two subtypes shared some genetic signals but did not overlap completely.
Frontiers in immunology
Context imageA pooled analysis of two phase 3 trials examined ruxolitinib cream outcomes across baseline patient characteristics. Among participants who used active cream from the start, 50.3% reached at least 75% improvement in facial VASI at one year.
Dermatology and therapy
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Every story links to an actual publication. Context photographs are labeled and credited. Research summaries include limitations and do not provide individual treatment advice.